Stability of Eye Drops Containing Adrenocortical Hormones in Light-Resistant Packages
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چکیده
منابع مشابه
Technology of eye drops containing metronidazole.
The aim of the studies was to determine the stability of metronidazole using UV spectrophotometric method in 0.5% w/w eye drops which were prepared under aseptic conditions and thermally sterilized. 0.9% solution of NaCl, 5% glucose and phosphate buffers of pH 6.97 and 6.81 were used as the solvents of metronidazole in the drops. Thiomersal and phenylmercuric borate were used to preserve the dr...
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OBJECTIVE Assessing the stability of cefazolin sodium in preservative-free and preservative-containing eye drops. METHOD Extemporaneous formulations of eye drops were prepared from a commercially-available parenteral product of cefazolin sodium: eye drops 'A' contained 50mg/ml of cefazolin sodium in 0.45% w/v sodium chloride solution, and eye drops 'B' contained 50 mg/ml, 0.005% w/v thiomersa...
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License. The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Permissions beyond the scope of the License are administered by Dove Medical Press Limited. Information on how to request permission may be f...
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The purpose of the studies was to examine the influence of the additives and storage temperature on physicochemical properties and on the antimicrobial activity of cefuroxime in the eye drops. The eye drops were 1% sterile aqueous solutions of cefuroxime in citrate buffer of pH 6.15-6.20, preserved with 0.002% thiomersal or 0.001% phenylmercuric borate with 0.4% beta-phenylethyl alcohol. Viscos...
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Suiphacetamide solutions at higher temperature degrade to its hydrolysed product, sulphanilamide, with a first-order rate constant. The degraded products are identified and characterised by chromatography and spectrophotometry. Attempts are made for the evaluation of kinetics, entropy and enthal changes activation energy and frequency factors during heating of sulphacetamide solutions. The dete...
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ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1979
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.5.95